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    CAPS Ca 2 dependent activator protein for secretion functions in priming Ca 2 dependent vesicle exocytosis but the regulation of CAPS activity has not been characterized Here we show that phosphorylation by protein kinase CK2 is required for CAPS activity Dephosphorylation eliminated CAPS activity in reconstituting Ca 2 dependent vesicle exocytosis in permeable and intact

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  • The Vesicle Priming Factor CAPS Functions as a Homodimer

    Neurotransmitters and peptide hormones are secreted by regulated vesicle exocytosis CAPS also known as CADPS is a 145 kDa cytosolic and peripheral membrane protein required for vesicle docking and priming steps that precede Ca2 triggered vesicle exocytosis CAPS binds phosphatidylinositol 4 5 bisphosphate PI 4 5 P2 and SNARE proteins and is proposed to promote SNARE protein complex

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    Repetition priming in the stop signal task The electrophysiology of sequential effects of stopping Author links open overlay panel J F E Oldenburg a C Roger a S Assecondi b F Verbruggen c W Fias a

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    2016 Petrie et al Journal of Biological Chemistry Neurotransmitters and peptide hormones are secreted by regulated vesicle exocytosis CAPS also known as CADPS is a 145 kDa cytosolic and peripheral membrane protein required for vesicle docking and priming

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  • The Vesicle Priming Factor CAPS Functions as a Homodimer

    Neurotransmitters and peptide hormones are secreted by regulated vesicle exocytosis CAPS also known as CADPS is a 145 kDa cytosolic and peripheral membrane protein required for vesicle docking and priming steps that precede Ca 2 triggered vesicle exocytosis CAPS binds phosphatidylinositol 4 5 bisphosphate PI 4 5 P 2 and SNARE proteins and is proposed to promote

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